Separation of Morphine and Glucuronated Metabolites on a Bonded Zwitterionic Stationary Phase
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چکیده
ZIC®-HILIC Columns The ZIC®-HILIC columns have a sulfobetaine type zwitterionic stationary phase covalently attached to 200 Å pore size and 5 μm particle size silica (see Figure 1). The permanently charged, yet overall neutral, highly polar zwitterionic column provides a unique environment particularly capable of solvating polar and charged compounds, which enables high-performance HILIC separations. The column can provide a selectivity benefiting from both hydrophilic and weak electrostatic interactions, while maintaining a low eluent ionic strength, making the column an ideal choice for LC/MS analysis.
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تاریخ انتشار 2003